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Ulrich Bierbach Selected Research

1- (2- (acridin- 9- ylamino)ethyl)- 1,3- dimethylthiourea

1/2013PT-ACRAMTU, a platinum-acridine anticancer agent, lengthens and aggregates, but does not stiffen or soften DNA.
7/2010Probing platinum-adenine-n3 adduct formation with DNA minor-groove binding agents.
10/2005Platinum-acridinylthiourea conjugates show cell line-specific cytotoxic enhancement in H460 lung carcinoma cells compared to cisplatin.
1/2005A non-crosslinking platinum-acridine hybrid agent shows enhanced cytotoxicity compared to clinical BCNU and cisplatin in glioblastoma cells.

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Ulrich Bierbach Research Topics

Disease

18Neoplasms (Cancer)
10/2021 - 12/2002
9Lung Neoplasms (Lung Cancer)
10/2021 - 10/2005
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2014 - 07/2008
3Adenocarcinoma of Lung
01/2021 - 12/2014
3Breast Neoplasms (Breast Cancer)
12/2016 - 09/2012
3Leukemia
07/2009 - 12/2002
2Glioblastoma (Glioblastoma Multiforme)
01/2005 - 03/2003
1Colonic Neoplasms (Colon Cancer)
01/2020
1Autoimmune Diseases (Autoimmune Disease)
05/2017
1Pancreatic Neoplasms (Pancreatic Cancer)
03/2017
1Ovarian Neoplasms (Ovarian Cancer)
09/2012
1Carcinoma (Carcinomatosis)
10/2005

Drug/Important Bio-Agent (IBA)

19PlatinumIBA
10/2021 - 12/2002
12AcridinesIBA
10/2021 - 12/2002
11Cisplatin (Platino)FDA LinkGeneric
11/2015 - 06/2004
9DNA (Deoxyribonucleic Acid)IBA
10/2021 - 12/2002
7Pharmaceutical PreparationsIBA
07/2019 - 01/2004
5Antineoplastic Agents (Antineoplastics)IBA
10/2021 - 07/2012
4Biological ProductsIBA
04/2015 - 03/2003
41- (2- (acridin- 9- ylamino)ethyl)- 1,3- dimethylthioureaIBA
01/2013 - 01/2005
3GoldIBA
05/2017 - 11/2009
2EstersIBA
12/2014 - 09/2012
2A-Form DNA (A-DNA)IBA
03/2013 - 10/2011
2DNA AdductsIBA
07/2012 - 10/2011
2ThioureaIBA
12/2008 - 07/2008
1Ribosomal RNAIBA
10/2021
1AzidesIBA
10/2021
1Liposomes (Liposome)IBA
01/2021
1EED226IBA
01/2020
1Membrane Transport Proteins (Biological Pump)IBA
01/2020
1tazemetostatIBA
01/2020
1Proteins (Proteins, Gene)FDA Link
01/2020
1LipidsIBA
03/2017
1Drug CarriersIBA
12/2016
1SolutionsIBA
12/2016
1Gefitinib (Iressa)FDA Link
04/2015
1LigandsIBA
04/2015
1RNA Polymerase I (Polymerase I, RNA)IBA
09/2013
1CarbamatesIBA
03/2013
1Hormones (Hormone)IBA
03/2013
1Estrogen ReceptorsIBA
03/2013
14-hydroxy-N-desmethyltamoxifenIBA
03/2013
1ChloridesIBA
09/2012
1NucleotidesIBA
07/2012
1EthaneIBA
08/2011
1CationsIBA
08/2011
1DiaminesIBA
08/2011
1NetropsinIBA
07/2010
1ethylenediamine (ethylenediamine dihydroiodide)FDA Link
07/2009
1Intercalating AgentsIBA
07/2008
1Cytotoxins (Cytolysins)IBA
07/2008
1Guanidine (Guanidine Nitrate)FDA Link
07/2008
1Carmustine (FIVB)FDA Link
01/2005

Therapy/Procedure

3Drug Therapy (Chemotherapy)
01/2020 - 01/2004
1Photothermal Therapy
12/2016